Acetyl_CoA_acetyltransferase -> Acetoacetyl_CoA Acetyl_CoA -> Acetoacetyl_CoA mSREBP -> HMG_CoA_Reductase_gene Dimethyl_allyl_pyrophosphate -> Geranyl_pyrophosphate Isopentenyl_pyrophosphate -> Geranyl_pyrophosphate Mevalonyl_pyrophosphate -> Isopentenyl_pyrophosphate Cyp51_RNA -> Cyp51 HMG_CoA_Synthase_gene -> HMG_CoA_Synthase_RNA Statins -> Statins Acetyl_CoA_acetyltransferase_RNA -> Acetyl_CoA_acetyltransferase Cholesterol -| Insig_SREBP_SCAP HMG_CoA_Synthase_RNA -> HMG_CoA_Synthase Insig_SREBP_SCAP -> SREBP_SCAP Statins -| SREBP_SCAP mSREBP -> Cyp51_gene pSREBP -> mSREBP Desmosterol -> Cholesterol Septdehydrocholesterol -> Cholesterol SREBP_SCAP -> pSREBP Lanosterol -> Desmosterol Acetyl_CoA_acetyltransferase_gene -> Acetyl_CoA_acetyltransferase_RNA FPP_Synthase_RNA -> FPP_Synthase Acetyl_CoA -> HMG_CoA Acetoacetyl_CoA -> HMG_CoA HMG_CoA_Synthase -> HMG_CoA HMG_CoA -> Mevalonic_Acid HMG_CoA_Reductase -> Mevalonic_Acid Isopentenyl_pyrophosphate -> Dimethyl_allyl_pyrophosphate FPP_Synthase_gene -> FPP_Synthase_RNA Lanosterol -> Septdehydrocholesterol HMG_CoA_Reductase_RNA -> HMG_CoA_Reductase Statins -| HMG_CoA_Reductase Squaline -> Lanosterol HMG_CoA_Reductase_gene -> HMG_CoA_Reductase_RNA mSREBP -> HMG_CoA_Synthase_gene Mevalonic_Acid -> Mevalonyl_pyrophosphate Acetyl_CoA -> Acetyl_CoA Cyp51_gene -> Cyp51_RNA Geranyl_pyrophosphate -> Farnesyl_pyrophosphate FPP_Synthase -| Farnesyl_pyrophosphate Farnesyl_pyrophosphate -> Squaline mSREBP -> Acetyl_CoA_acetyltransferase_gene mSREBP -> FPP_Synthase_gene $Acetoacetyl_CoA: (Acetyl_CoA & Acetyl_CoA_acetyltransferase) $Acetyl_CoA: Acetyl_CoA $Acetyl_CoA_acetyltransferase: Acetyl_CoA_acetyltransferase_RNA $Acetyl_CoA_acetyltransferase_RNA: Acetyl_CoA_acetyltransferase_gene $Acetyl_CoA_acetyltransferase_gene: mSREBP $Cholesterol: (Desmosterol | Septdehydrocholesterol) $Cyp51: Cyp51_RNA $Cyp51_RNA: Cyp51_gene $Cyp51_gene: mSREBP $Desmosterol: Lanosterol $Dimethyl_allyl_pyrophosphate: Isopentenyl_pyrophosphate $FPP_Synthase: FPP_Synthase_RNA $FPP_Synthase_RNA: FPP_Synthase_gene $FPP_Synthase_gene: mSREBP $Farnesyl_pyrophosphate: (Geranyl_pyrophosphate & !FPP_Synthase) $Geranyl_pyrophosphate: (Isopentenyl_pyrophosphate | Dimethyl_allyl_pyrophosphate) $HMG_CoA: (Acetoacetyl_CoA & (Acetyl_CoA & HMG_CoA_Synthase)) $HMG_CoA_Reductase: (HMG_CoA_Reductase_RNA & !Statins) $HMG_CoA_Reductase_RNA: HMG_CoA_Reductase_gene $HMG_CoA_Reductase_gene: mSREBP $HMG_CoA_Synthase: HMG_CoA_Synthase_RNA $HMG_CoA_Synthase_RNA: HMG_CoA_Synthase_gene $HMG_CoA_Synthase_gene: mSREBP $Insig_SREBP_SCAP: !Cholesterol $Isopentenyl_pyrophosphate: Mevalonyl_pyrophosphate $Lanosterol: Squaline $Mevalonic_Acid: (HMG_CoA & HMG_CoA_Reductase) $Mevalonyl_pyrophosphate: Mevalonic_Acid $SREBP_SCAP: (Insig_SREBP_SCAP & !Statins) $Septdehydrocholesterol: Lanosterol $Squaline: Farnesyl_pyrophosphate $Statins: Statins $mSREBP: pSREBP $pSREBP: SREBP_SCAP